Exploration of Antibacterial Potential of Sonchus oleraceus L.

Abstract

The current research work was conducted to evaluate the medicinal potential of Sonchus oleraceus L, collected from Samahni, District Bhimber Azad Kashmir. In present study methanolic, chloroform, acetone and petroleum ether extract of S. oleraceus L. were screened for their antibacterial activity. The activity was checked by the disc diffusion method. The antibacterial activity of all the extracts were checked against five bacterial strains, collected from the Postgraduate Laboratory, Department of Biotechnology, Mirpur University of Science and Technology (MUST), Mirpur AJK. The strains include Staphylococcus aureus, Bacillus subtilis, Bacillus pumilus, Escherichia coli and Pseudomonas aeruginosa. The highest antibacterial activity of all four extracts was recorded against Staphylococcus aureus, with highest in methanolic extract (12.9±04mm). Study showed the presence of antibacterial properties in S. oleraceus L. which can be utilized to make novel drugs in pharmaceuticals industries for humans and animals.